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Preeclampsia Drug Reaches Clinical Trial Phase

Researchers at Lund University in Sweden have published a study in the journal Scientific Reports that suggests a drug (alpha-1-microglobulin or A1M) has potential therapeutic effects in patients with preeclampsia. In tests, researchers found that A1M stopped the leakage of protein in the kidneys and improved organ function in the kidneys and the placenta.

Preeclampsia is characterized by the development of high blood pressure and high protein levels in urine at or after 20 weeks of pregnancy. It is a serious complication that can result in maternal and fetal injury or death. An investigation undertaken by USA Today suggests that high blood pressure is a leading cause of mothers dying and suffering strokes—and as many as 60% of maternal deaths due to hypertension could have been prevented.   

Patient trials were launched after researchers saw no indication of side effects, and the results confirmed previous studies by the research team. 

“This feels like a milestone in our research,” senior researcher Lena Erlandsson said of the clinical trials. 

A date has not yet been set for a potential drug to come to market, as the research and development of pharmaceuticals takes many years. However, the results of this study are promising and suggest there may be a treatment for the condition that annually affects around 9 million pregnant women worldwide. 

Pregnant women with preeclampsia are at risk for seizures and the development of eclampsia (coma), stroke, severe bleeding, heart attack, cardiovascular disease, kidney disease, and placental abruption. If severe preeclampsia develops, the mother will require hospitalization.  However, mild preeclampsia may be managed with at-home care and close physician monitoring.  

Symptoms of preeclampsia may include headaches, blurred vision, upper abdominal pain, decreased urine output, low blood platelet level, and sudden weight gain, and should be discussed with a physician.

If you experienced preeclampsia during your pregnancy, and you or your child suffered injury as a result, please contact us at 877-262-9767.

 

The following reviews from our clients do not constitute a guarantee, warranty, or prediction regarding the outcome of another legal matter. The cases mentioned in the reviews are illustrative of some of the matters previously handled by Grant & Eisenhofer involving various areas of birth injury law. These reviews are endorsements.

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The following reviews from our clients do not constitute a guarantee, warranty, or prediction regarding the outcome of another legal matter. The cases mentioned in the reviews are illustrative of some of the matters previously handled by Grant & Eisenhofer involving various areas of birth injury law. These reviews are endorsements.

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